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Record W1682622845 · doi:10.3233/bir-2009-0538

Rethinking turbulence in blood

2009· article· en· W1682622845 on OpenAlexaff
Luca Antiga, David A. Steinman

Bibliographic record

VenueBiorheology · 2009
Typearticle
Languageen
FieldMedicine
TopicBlood properties and coagulation
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsTurbulenceMechanicsEddyReynolds numberKolmogorov microscalesLaminar flowPhysicsClassical mechanicsVortexK-epsilon turbulence modelK-omega turbulence model

Abstract

fetched live from OpenAlex

Blood flow, normally laminar, can exhibit high frequency fluctuations suggesting turbulence, which has important implications for the pathophysiology of vascular diseases and the design of blood-bearing devices. According to the classical model of turbulence in a homogeneous fluid, these fluctuations can be attributed to the cascade of eddies down to the Kolmogorov length scale, which, for apparent turbulence in blood, is reported to be on the order of tens of microns. On the other hand, blood is a suspension of mostly red blood cells (RBC), the size and concentration of which would seem to preclude the formation of eddies down to these scales. Assuming dissipation occurs instead via cell-cell interactions mediated by the plasma, here we show how turbulent velocity fluctuations, normally ascribed to turbulent (Reynolds) stresses, could give rise to viscous shear stresses. This may help to resolve fundamental inconsistencies in the understanding of mechanical hemolysis, and it provides a physical basis for the forces actually experienced by formed elements in the blood under nominally turbulent flow. In summary, RBC must be acknowledged as equal players if a satisfactory definition of turbulence in blood is to be achieved.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0010.003
Scholarly communication0.0020.002
Open science0.0000.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.256
Teacher spread0.233 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations126
Published2009
Admission routes1
Has abstractyes

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