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Record W1692526950 · doi:10.1002/pds.2318

Mini‐Sentinel's systematic reviews of validated methods for identifying health outcomes using administrative data: summary of findings and suggestions for future research

2012· article· en· W1692526950 on OpenAlexfundno aff
Ryan M. Carnahan

Bibliographic record

VenuePharmacoepidemiology and Drug Safety · 2012
Typearticle
Languageen
FieldDecision Sciences
TopicMeta-analysis and systematic reviews
Canadian institutionsnot available
FundersHamilton Health Sciences FoundationU.S. Department of Health and Human Services
KeywordsMedicineGeneralizability theorySystematic reviewExternal validityPharmacoepidemiologyMEDLINEData miningComputer scienceStatistics

Abstract

fetched live from OpenAlex

PURPOSE: The validity of findings from surveillance activities, which use administrative and claims data to link exposures to adverse events, depends in part on the validity of algorithms to identify health outcomes using these data. This review provides a high level overview of the findings of 19 systematic reviews of studies, which have examined the validity of algorithms to identify health outcomes using these data. The author categorized outcomes on the basis of the strength of evidence supporting valid algorithms to identify acute or incident events and suggested priorities for future validation studies. METHODS: The 19 reviews were evaluated, and key findings and suggestions for future research were summarized by a single reviewer. Outcomes with algorithms that consistently identified acute events or incident conditions with positive predictive values of greater than 70% across multiple studies and populations are described as low priority for future algorithm validation studies. RESULTS: Algorithms to identify cerebrovascular accidents, transient ischemic attacks, congestive heart failure, deep vein thrombosis, pulmonary embolism, angioedema, and total hip arthroplasty revision performed well across multiple studies and are considered low priority for future validation studies. Other outcomes were generally thought to require additional validation studies or algorithm refinement to be confident in algorithms. Few studies examined the validity of International Classification of Diseases, 10th Revision, codes. CONCLUSION: Users of these reviews need to consider the generalizability of findings to their study populations. For some outcomes with poorly performing codes, it may always be necessary to validate cases.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.147
metaresearch head score (Gemma)0.384
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Systematic review · Consensus signal: Systematic review
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.853
Threshold uncertainty score0.777

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1470.384
Meta-epidemiology (narrow)0.0030.003
Meta-epidemiology (broad)0.0110.018
Bibliometrics0.0260.019
Science and technology studies0.0010.002
Scholarly communication0.0060.008
Open science0.0040.005
Research integrity0.0040.003
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.946
GPT teacher head0.740
Teacher spread0.206 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designSystematic review
DomainMethods
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations76
Published2012
Admission routes1
Has abstractyes

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