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Record W174967433 · doi:10.1136/bmj.326.7390.658

The making of a disease: female sexual dysfunction

2003· letter· en· W174967433 on OpenAlexaff
Rosemary Basson

Bibliographic record

VenueBMJ · 2003
Typeletter
Languageen
FieldMedicine
TopicSexual function and dysfunction studies
Canadian institutionsVancouver Hospital and Health Sciences CentreUniversity of British Columbia
Fundersnot available
KeywordsSexual dysfunctionSexual functionHuman sexualityFemale sexual dysfunctionDiseaseMedicineEtiologyPsychological interventionPsychiatryPsychologyClinical psychologyGynecologyPathologyInternal medicine

Abstract

fetched live from OpenAlex

Editor—Moynihan wrote about female sexual dysfunction as a disease in the making.1 As co-chairs for an (unpaid) international committee, commissioned and supported by the American Foundation of Urological Disease, to improve definitions of women's sexual dysfunction, we regret the sensational biased view of industry funded research of biological components of women's sexual function. The common error of equating self reported sexual problems with medically diagnosable disorder is well recognised. However, to focus only on this and neglect the need for research into aetiology, pathogenesis, and treatment of women's sexual dysfunction from disease, medical, and surgical interventions, is unfortunate. To date, neither the major neurotransmitter involved in vaginal congestion nor the autonomic innervation of the vulval structures has been established. Industry funding facilitates research of interrupted sexual responses from chemotherapy, pelvic surgery, neurological disease, premature menopause, and drug treatment, as well as healthy sexual physiology. We question the concept of a “new definition of human illness.” Women's sexual dysfunction has been diagnosed throughout the centuries. The committee meeting in 1998 tried to modulate definitions in the American Psychiatric Association's Diagnostic and Statistical Manual of Disease, to be more reflective of women's sexuality and did not create “new disorders.” However, the formulation of accurate diagnosis is a continuing process—what is “normal” for women of different ethnic, religious, and cultural backgrounds, and of different ages and life stages is still unclear. Women's sexual function is highly contextual; many aetiological factors—physical, psychological, and interpersonal—must be not only evaluated but included in the diagnosis. Thus the definitions are becoming less rather than more medical. Without accurate definitions of dysfunction, any potential contributory role for pharmacotherapy in holistic management of dysfunction cannot be explored. Without support from the pharmaceutical industry, little new research into sexual physiology is likely or the means by which psychological factors alter the biological processes involved.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.014
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.998
Threshold uncertainty score0.013

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.014
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0010.001
Science and technology studies0.0020.003
Scholarly communication0.0030.005
Open science0.0020.001
Research integrity0.0100.017
Insufficient payload (model declined to judge)0.0040.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.061
GPT teacher head0.335
Teacher spread0.274 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2003
Admission routes1
Has abstractyes

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