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Association Between ADHD and Obesity: A Systematic Review and Meta-Analysis

2015· review· en· 587 citations· W1888633954 on OpenAlex· 10.1176/appi.ajp.2015.15020266

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About CanadaIts subject is Canada, wherever its authors sit.

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Opus teacher head0.102
GPT teacher head0.408
Teacher spread
0.306 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

OBJECTIVE: Impulsivity and inattention related to attention deficit hyperactivity disorder (ADHD) may increase food intake and, consequently, weight gain. However, findings on the association between obesity/overweight and ADHD are mixed. The authors conducted a meta-analysis to estimate this association. METHOD: A broad range of databases was searched through Aug. 31, 2014. Unpublished studies were also obtained. Study quality was rated with the Newcastle-Ottawa Scale. Random-effects models were used. RESULTS: Forty-two studies that included a total of 728,136 individuals (48,161 ADHD subjects; 679,975 comparison subjects) were retained. A significant association between obesity and ADHD was found for both children (odds ratio=1.20, 95% CI=1.05-1.37) and adults (odds ratio=1.55, 95% CI=1.32-1.81). The pooled prevalence of obesity was increased by about 70% in adults with ADHD (28.2%, 95% CI=22.8-34.4) compared with those without ADHD (16.4%, 95% CI=13.4-19.9), and by about 40% in children with ADHD (10.3%, 95% CI=7.9-13.3) compared with those without ADHD (7.4%, 95% CI=5.4-10.1). The significant association between ADHD and obesity remained when limited to studies 1) reporting odds ratios adjusted for possible confounding factors; 2) diagnosing ADHD by direct interview; and 3) using directly measured height and weight. Gender, study setting, study country, and study quality did not moderate the association between obesity and ADHD. ADHD was also significantly associated with overweight. Individuals medicated for ADHD were not at higher risk of obesity. CONCLUSIONS: This study provides meta-analytic evidence for a significant association between ADHD and obesity/overweight. Further research should address possible underlying mechanisms and the long-term effects of ADHD treatments on weight in individuals with both ADHD and obesity.

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The record

Venue
American Journal of Psychiatry
Topic
Attention Deficit Hyperactivity Disorder
Field
Medicine
Canadian institutions
Funders
National Institutes of HealthCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorHospital de Clínicas de Porto AlegrePfizerCilagUniversity of OxfordEli Lilly and Company
Keywords
Odds ratioObesityOverweightImpulsivityConfoundingAttention deficit hyperactivity disorderMedicineMeta-analysisPsychiatryInternal medicine
Has abstract in OpenAlex
yes