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Record W1964946187 · doi:10.1136/ebn.4.2.36

Clinically useful measures of the effects of treatment

2001· article· en· W1964946187 on OpenAlexaff
Alba DiCenso

Bibliographic record

VenueEvidence-Based Nursing · 2001
Typearticle
Languageen
FieldMedicine
TopicDementia and Cognitive Impairment Research
Canadian institutionsMcMaster University
Fundersnot available
KeywordsNumber needed to treatMedicinePsychological interventionAbsolute risk reductionTreatment effectPsychologyRelative riskNursingConfidence interval

Abstract

fetched live from OpenAlex

In the EBN notebooks that have appeared in the previous 2 issues of the journal, we outlined 3 steps to help us to determine whether to apply the results of a research study to our patients.1 Firstly, we should consider whether the study results are valid. For articles about the effectiveness of healthcare interventions, the 3 key validity issues are whether the patients were randomly assigned to different treatments, whether they were analysed according to the groups to which they were assigned, and the extent of follow up. Secondly, if we judge the study to be valid, we examine the study results to determine whether the new treatment is effective, the size of the effect, and whether the effect is clinically important. When determining the clinical significance of effective treatments, findings can be expressed in 3 ways: as a change in relative risk, change in absolute risk and number needed to treat (NNT). Abstracts in Evidence-Based Nursing that describe effective treatments include these numbers, when data permit their calculation. The third step, the application to an individual patient, requires knowledge about both the study and the patient. This involves consideration of both the extent to which the patient resembles those who were enrolled in the study and the patient's risk for the event for which the treatment was designed.2 This notebook will explain the concepts that help us to determine whether study findings should be applied to our own individual patients. Let's work through a randomised controlled trial abstracted in this issue of the journal (p52) that evaluates the effectiveness of a cognitive behavioural family intervention in reducing psychological distress and depression in caregivers of patients with Alzheimer's disease.3 Addressing first the validity of this trial, we find that patient-caregiver dyads were randomly assigned to the 14 …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.044
metaresearch head score (Gemma)0.169
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.044
Threshold uncertainty score0.232

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0440.169
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0020.004
Bibliometrics0.0060.004
Science and technology studies0.0010.002
Scholarly communication0.0030.004
Open science0.0020.002
Research integrity0.0020.004
Insufficient payload (model declined to judge)0.0200.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.086
GPT teacher head0.389
Teacher spread0.303 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations28
Published2001
Admission routes1
Has abstractyes

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