Effect of Hypoxia on the Corneoretinal Potential in Man
Why this work is in the frame
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Bibliographic record
Abstract
We measured the effect of altered blood gases induced by breathing high and low oxygen-containing gases in man. The corneoretinal potential was recorded in 15 subjects during isocapnic hypoxia, hypocapnia and hyperoxia. Studies were first conducted in conditions of constant ambient luminance and later during repeated dark and light phases. Isocapnic hypoxia of a degree sufficient to induce arterial oxygen desaturation, reduced the dark trough by a mean ± SD of 49.8 ± 47.6 μV (p < 0.025) with a similar, but less consistent reduction in the light peak (mean = 78.5, SD = 80.8 μV; p < 0.05). By contrast, hyperoxia (PO<sub>2</sub> = 600 mm Hg) and hypocapnia (20–25 mm Hg) under conditions of normal oxygenation had no systematic influence on corneoretinal potential. We conclude that isocapnic hypoxia reduces the capacity of the corneoretinal potential to respond normally to dark and light stimuli but that these responses do not offer a clinically feasible means for noninvasive monitoring of cerebral oxygen delivery.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it