MétaCan
Menu
Back to cohort

Risks Associated with Herbal Medicinal Products

2002· article· de· W1972877570 on OpenAlexaff
E. Ernst, Max H Pittler

Bibliographic record

VenueWiener Medizinische Wochenschrift · 2002
Typearticle
Languagede
FieldPharmacology, Toxicology and Pharmaceutics
TopicDrug-Induced Hepatotoxicity and Protection
Canadian institutionsVictoria Park
Fundersnot available
KeywordsMedicinePopularityTraditional medicineDrugOrder (exchange)PharmacologyEnvironmental healthBusiness

Abstract

fetched live from OpenAlex

Health risks associated with the use of herbal medicinal products (HMPs) are often an emotionally discussed issue. The topic is, however, important not least because of the present popularity of HMPs. This article aims to provide a factual overview of this complex subject. The evidence relating to the toxicity, interactions and quality of a number of HMPs is reviewed. Toxicity data indicate that some HMPs have the potential to cause serious adverse events and fatalities. HMPs affect pharmacokinetic and pharmacodynamic factors and thus cause herb-drug interactions. Reports of HMPs affected by contamination, adulteration or substitution of botanical material have repeatedly caused concern. Asian HMPs are most often implicated. It is concluded that HMPs are not free of risk. More research and more information are required in order to maximize consumers' safety.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.222
GPT teacher head0.390
Teacher spread0.167 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations60
Published2002
Admission routes1
Has abstractyes

Explore more

Same venueWiener Medizinische WochenschriftSame topicDrug-Induced Hepatotoxicity and ProtectionFrench-language works237,207