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Drug Delivery Systems: Entering the Mainstream

2004· article· en· 4,508 citations· W2013470095 on OpenAlex· 10.1126/science.1095833

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Abstract

Drug delivery systems (DDS) such as lipid- or polymer-based nanoparticles can be designed to improve the pharmacological and therapeutic properties of drugs administered parenterally. Many of the early problems that hindered the clinical applications of particulate DDS have been overcome, with several DDS formulations of anticancer and antifungal drugs now approved for clinical use. Furthermore, there is considerable interest in exploiting the advantages of DDS for in vivo delivery of new drugs derived from proteomics or genomics research and for their use in ligand-targeted therapeutics.

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The record

Venue
Science
Topic
Nanoparticle-Based Drug Delivery
Field
Materials Science
Canadian institutions
Inimex Pharmaceuticals (Canada)University of AlbertaUniversity of British Columbia
Funders
Keywords
Drug deliveryDrugTargeted drug deliveryPharmacologyAntifungalMedicineComputational biologyNanotechnologyBiologyMaterials science
Has abstract in OpenAlex
yes