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Record W2013598665 · doi:10.1093/imamat/hxl028

The stability and dynamics of a spike in the 1D Keller–Segel model

2007· article· en· W2013598665 on OpenAlexaff
Ki‐Woon Kang, Théodore Kolokolnikov, Michael J. Ward

Bibliographic record

VenueIMA Journal of Applied Mathematics · 2007
Typearticle
Languageen
FieldMathematics
TopicMathematical Biology Tumor Growth
Canadian institutionsDalhousie UniversityUniversity of British ColumbiaToronto Metropolitan University
FundersSan Diego State University
KeywordsEigenvalues and eigenvectorsSpike (software development)Mathematical analysisMetastabilityDomain (mathematical analysis)MathematicsExponential stabilityOrdinary differential equationStability (learning theory)PhysicsStability theoryStatistical physicsDifferential equationNonlinear systemQuantum mechanics

Abstract

fetched live from OpenAlex

In the limit of a large mass M ≫ 1 and on a finite interval of length 2L, an equilibrium spike solution to the classical Keller–Segel chemotaxis model with a linear chemotactic function is constructed asymptotically. By calculating an asymptotic formula for the translational eigenvalue for M ≫ 1, it is shown that the equilibrium spike solution is unstable to translations of the spike profile. If in addition L ≫ 1, the equilibrium spike is shown to be metastable as a result of an asymptotically exponentially small eigenvalue. For M ≫ 1 and L ≫ 1, an asymptotic ordinary differential equation for the metastable spike motion is derived that shows that the spike drifts exponentially slowly towards one of the boundaries of the domain. For a certain reduced Keller–Segel model, corresponding to a domain of small length, a solution with a spike at each of the two boundaries is constructed. This solution is found to be metastable, and it is shown that there is an exponentially slow exchange of mass between the two spikes that occurs over very long timescales. For arbitrary initial conditions, energy methods are used to show the global existence of solutions. The relationship between this reduced Keller–Segel model and a Burgers-type equation modelling the upward propagation of a flame front in a finite channel is emphasized. Full numerical computations are used to confirm the asymptotic results.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.005
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0010.000
Science and technology studies0.0010.002
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.033
GPT teacher head0.295
Teacher spread0.262 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations36
Published2007
Admission routes1
Has abstractyes

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