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Record W2017496269 · doi:10.1002/ddr.20423

How does NICE value innovation?

2010· article· en· W2017496269 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueDrug Development Research · 2010
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsCARE Canada
Fundersnot available
KeywordsNiceExcellenceIncentiveValue (mathematics)Government (linguistics)BusinessPsychological interventionPublic relationsMedicinePublic economicsActuarial scienceMarketingEconomicsPolitical scienceNursing

Abstract

fetched live from OpenAlex

Abstract No country can afford all the health care interventions that might benefit patients. Demand will always outstrip available resources, so priorities have to be agreed upon. Such decisions are controversial, making it vital that they are underpinned by robust transparent processes and methods. In the United Kingdom, this is the responsibility of the National Institute for Health and Clinical Excellence (NICE). In 2009, in response to challenges that NICE was not giving sufficient value to innovation, an independent enquiry was undertaken by Sir Ian Kennedy. The enquiry raised important questions about whether NICE should only offer incentives for innovation when the benefits are actually seen by the National Health Service (NHS) as improved outcomes for patients, or whether future, but as yet unrealized, benefits such as the subsequent development of the next generation of drugs should be taken into account. There is a UK government commitment to value‐based pricing but questions remain about how this could value innovation. Potential solutions are an increased use of NICE's “only in research” recommendations and exploration of novel trial designs. Drug Dev Res 71: 449–456, 2010. © 2010 Wiley‐Liss, Inc.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.054
metaresearch head score (Gemma)0.009
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Insufficient payload (model declined to judge)
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.843
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0540.009
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.000
Scholarly communication0.0000.001
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.005

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.428
GPT teacher head0.500
Teacher spread0.071 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it