Randomized trial of behavioral activation, cognitive therapy, and antidepressant medication in the acute treatment of adults with major depression.
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- Teacher spread
- 0.374 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
Antidepressant medication is considered the current standard for severe depression, and cognitive therapy is the most widely investigated psychosocial treatment for depression. However, not all patients want to take medication, and cognitive therapy has not demonstrated consistent efficacy across trials. Moreover, dismantling designs have suggested that behavioral components may account for the efficacy of cognitive therapy. The present study tested the efficacy of behavioral activation by comparing it with cognitive therapy and antidepressant medication in a randomized placebo-controlled design in adults with major depressive disorder (N = 241). In addition, it examined the importance of initial severity as a moderator of treatment outcome. Among more severely depressed patients, behavioral activation was comparable to antidepressant medication, and both significantly outperformed cognitive therapy. The implications of these findings for the evaluation of current treatment guidelines and dissemination are discussed.
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The record
- Venue
- Journal of Consulting and Clinical Psychology
- Topic
- Treatment of Major Depression
- Field
- Medicine
- Canadian institutions
- University of Calgary
- Funders
- National Institute of Mental Health
- Keywords
- Cognitive behavioral therapyPsychosocialRandomized controlled trialCognitive therapyBehavioral activationAntidepressantPsychologyDepression (economics)CognitionPlaceboPsychiatryMajor depressive disorderClinical psychologyCognitive restructuringMedicineAnxietyInternal medicineAlternative medicine
- Has abstract in OpenAlex
- yes