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Record W2039746571 · doi:10.1109/ichit.2006.211

Rough Discretization of Gene Expression Data

2006· article· en· W2039746571 on OpenAlexaff
Dominik Ślȩzak, Jakub Wróblewski

Bibliographic record

VenueInternational Conference on Hybrid Information Technology · 2006
Typearticle
Languageen
FieldComputer Science
TopicRough Sets and Fuzzy Logic
Canadian institutionsUniversity of Regina
Fundersnot available
KeywordsRough setDiscretizationData miningObject (grammar)Reduction (mathematics)Set (abstract data type)Computer scienceExpression (computer science)MathematicsAlgorithmArtificial intelligence

Abstract

fetched live from OpenAlex

We adapt the rough set-based approach to deal with the gene expression data, where the problem is a huge amount of genes (attributes) a?A versus small amount of experiments (objects) u?U. We perform the gene reduction using standard rough set methodology based on approximate decision reducts applied against specially prepared data. We use rough discretization - Every pair of objects (x,y)xU yields a new object, which takes values \ge a(x) if and only if a(y)\ge a(x); and \le a(x) otherwise; over original genes-attributes aA. In this way: 1) We work with desired, larger number of objects improving credibility of the obtained reducts; 2) We produce more decision rules, which vote during classification of new observations; 3) We avoid an issue of discretization of real-valued attributes, difficult and leading to unpredictable results in case of any data sets having much more attributes than objects. We illustrate our method by analysis of the gene expression data related to breast cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: Simulation or modeling
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.002
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0020.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0020.002
Science and technology studies0.0000.001
Scholarly communication0.0020.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.268
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2006
Admission routes1
Has abstractyes

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