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Re-evaluating the Transfusion Trigger: How Low Is Safe?

2002· review· en· W2050899809 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAmerican Journal of Therapeutics · 2002
Typereview
Languageen
FieldMedicine
TopicBlood transfusion and management
Canadian institutionsOttawa HospitalUniversity of Ottawa
Fundersnot available
KeywordsMedicineLimitingAnemiaIntensive care medicineBlood transfusionDonationDiseaseClinical PracticeEmergency medicineSurgeryInternal medicinePhysical therapy

Abstract

fetched live from OpenAlex

Concerns about transfusion-associated complications, in particular viral transmission, have motivated a more restrained pattern of clinical transfusion practice. This change in practice has allowed for an evaluation of the risks of withholding transfusion and the benefits of providing transfusion. The recognized risks of transfusion have declined, and this reduction in risks has been brought about by improved screening, better testing strategies and tests, and leuko-reduction at the time of donation. There are benefits to transfusion, in limiting hypoxic morbidity and mortality. These benefits are clearly evident only at very low levels of serum hemoglobin concentrations in healthy patients who tolerate moderate levels of anemia without morbidity. However, the benefits of transfusion are apparent at higher initial serum level concentrations in patients with cardiovascular disease who are less tolerant of anemia.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.994
Threshold uncertainty score0.988

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.128
GPT teacher head0.396
Teacher spread0.268 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it