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Record W2060552609 · doi:10.1016/j.procs.2012.04.180

Kepler for ‘Omics Bioinformatics

2012· article· en· W2060552609 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueProcedia Computer Science · 2012
Typearticle
Languageen
FieldDecision Sciences
TopicScientific Computing and Data Management
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsComputer scienceOmicsKeplerBioinformaticsData scienceComputational biologyBiology

Abstract

fetched live from OpenAlex

Abstract There has been a massive increase in the number of large scale biological datasets during the past twenty years, producing new challenges and complexities for analysis. Many of these new datasets are in the ‘omics fields, involving analysis of the genome, transcriptome, and proteome among others. Here, we review ‘omics community-specific factors affecting use of bioinformatics workflow systems. We identify the characteristics of the audience for scientific workflow systems in this community, the existence of a large amount of prewritten software, the use of large amounts of data in a typical analysis, and the growing complexity of analyses as important factors in considering workflow design criteria in this field and also future development of Kepler. Generally, many factors favor much increased use of Kepler in bioinformatics in the future, in particular its advantages in comprehensibility, extensibility, and modifiability of bioinformatics pipelines. We suggest concrete steps to enable further use of this flexible workflow system in ‘omics analyses.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.012
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScholarly communication
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.832
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0120.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.000
Scholarly communication0.0010.002
Open science0.0030.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.162
GPT teacher head0.391
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it