Costos en pacientes con infección por Acinetobacter baumannii en Colombia
Bibliographic record
Abstract
Determinar el impacto económico como resultado de la adquisición de una infección por A. baumannii en Colombia. Se consideró la información de un estudio previo de cohorte prospectivo, multicéntrico. Se incluyeron 165 pacientes ingresados en las Unidades de Cuidados Intensivos (UCIs) participantes entre abril de 2006 y abril de 2010. Se cuantificaron los costos directos e indirectos de la atención desde la perspectiva de la sociedad utilizando la técnica de micro-costeo, y se realizaron modelos uni y multivariados. La mayoría de los pacientes eran menores de 65 años de edad (75%), hombres (64%) y una tercera parte (32%) estaban infectados por un A. baumannii resistente (resistencia a 5 o más familias de antimicrobianos). El costo total hospitalario en la población de pacientes del estudio fue de US $ 10.180 (Costos directos US $ 10.105 SD ± 6.671 y costos indirectos US $ 75 ± 106 por paciente). El costo de los antimicrobianos fue de US $ 3.497 ± 3.510 por paciente. Los pacientes con A. baumannii que fueron ingresados en la UCI son altamente costosos para el sistema de salud Colombiano. Aunque el costo principal estuvo asociado directamente a la atención en salud, cada paciente y su familia también asumieron costos, que se estimaron aproximadamente en 30% del salario mensual mínimo legal vigente para el año 2012. The purpose of the study was to determine the healthcare costs among patients infected with A. baumannii in intensive care units (ICUs) in Colombia. We reviewed information from a previous prospective, observational, and multicenter study that included 165 patients admitted to Critical Care Units (ICUs) between April 2006 and April 2010. Direct and indirect health care costs were estimated from the societal perspective using micro-costing, and uni-and multivariate models were constructed. The majority of patients (64%) were male; most (75%) were under 65 years of age, and 32% were infected with a pathogen resistant to 5 or more antimicrobial families. Overall, the healthcare cost in our sample was US $10,180 (The total direct cost (SD) was US $10,105 ± $6671 and the indirect cost was US $75 ± $106 per patient). The antimicrobial cost was US $3,497 ± $3,510 per patient and indirect costs represented <1% of the total cost. High costs were observed in patients with A. baumannii who were admitted to the ICU. The main cost was the direct cost of care, but patients and their families assumed out-of-pocket costs as a consequence of the infection that represented nearly 30% of the legal minimum wage for Colombia in 2012.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".