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Record W2078583460 · doi:10.3934/dcdsb.2004.4.999

Modelling the effect of imperfect vaccines on disease epidemiology

2004· article· en· W2078583460 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueDiscrete and Continuous Dynamical Systems - B · 2004
Typearticle
Languageen
FieldMedicine
TopicMathematical and Theoretical Epidemiology and Ecology Models
Canadian institutionsNational Research Council CanadaNational Research Council Institute for Biodiagnostics
FundersNatural Sciences and Engineering Research Council of Canada
KeywordsImperfectBasic reproduction numberPiecewiseVaccinationInvariant (physics)Mathematical modelling of infectious diseaseEpidemic modelTransmission (telecommunications)DiseaseInfectious disease (medical specialty)MathematicsApplied mathematicsDisease transmissionEconometricsComputer scienceMedicineVirologyEnvironmental healthMathematical analysisPopulationInternal medicine

Abstract

fetched live from OpenAlex

We develop a mathematical model to monitor the effect of imperfectvaccines on the transmission dynamics of infectious diseases. It isassumed that the vaccine efficacy is not $100\%$ and may wane withtime. The model will be analyzed using a new technique based on someresults related to the Poincaré index of a piecewise smooth Jordancurve defined as the boundary of a positively invariant region forthe model. Using global analysis of the model, it is shown thatreducing the basic reproductive number ($\mathcal{R}_0$) to values less thanone no longer guarantees disease eradication. This analysis isextended to determine the threshold level of vaccination coveragethat guarantees disease eradication.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.878
Threshold uncertainty score0.405

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.014
GPT teacher head0.279
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it