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Record W2095335319 · doi:10.2135/cropsci2014.03.0249

Perspectives for Genomic Selection Applications and Research in Plants

2014· article· en· W2095335319 on OpenAlexfundno aff
Nicolas Heslot, Jean‐Luc Jannink, Mark E. Sorrells

Bibliographic record

VenueCrop Science · 2014
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and phenotypic traits in livestock
Canadian institutionsnot available
FundersHatchU.S. Department of Agriculture
KeywordsSelection (genetic algorithm)Genomic selectionBiologyTraitResource (disambiguation)PopulationGenetic gainQuantitative trait locusBiotechnologyPlant breedingMarker-assisted selectionAsset (computer security)Computational biologyComputer scienceGeneticsMachine learningGenotypeGenetic variationGene

Abstract

fetched live from OpenAlex

ABSTRACT Genomic selection (GS) has created a lot of excitement and expectations in the animal‐ and plant‐breeding research communities. In this review, we briefly describe how genomic prediction can be integrated into breeding efforts and point out achievements and areas where more research is needed. Genomic selection provides many opportunities to increase genetic gain in plant breeding per unit time and cost. Early empirical and simulation results are promising, but for GS to deliver genetic gains, careful consideration of the problem of optimal resource allocation is needed. Consideration of the cost‐benefit balance of using markers for each trait and stage of the breeding cycle is needed, moving beyond only focusing on recurrent selection with GS on a few complex traits, using prediction on unphenotyped individuals. With decreasing marker cost, phenotype data is quickly becoming the most valuable asset and marker‐assisted selection strategies should focus on making the most of scarce and expensive phenotypes. It is important to realize that markers can also improve accuracy of selection for phenotyped individuals. Use of markers as an aid to phenotype analysis suggests a number of new strategies in terms of experimental design and multi‐trait models. GS also provides new ways to analyze and deal with genotype by environment interactions. Lastly, we point to some recent results showing that new models are needed to improve predictions particularly with respect to the use of distantly related individuals in the training population.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.011
metaresearch head score (Gemma)0.009
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.012
Threshold uncertainty score0.058

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0110.009
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.005
Scholarly communication0.0030.004
Open science0.0020.002
Research integrity0.0040.004
Insufficient payload (model declined to judge)0.0120.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.028
GPT teacher head0.333
Teacher spread0.306 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations415
Published2014
Admission routes1
Has abstractyes

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Same venueCrop ScienceSame topicGenetic and phenotypic traits in livestockFrench-language works237,207