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Record W2111077861 · doi:10.1142/s0218202504003726

THE LANGEVIN OR KRAMERS APPROACH TO BIOLOGICAL MODELING

2004· article· en· W2111077861 on OpenAlexaff
K. P. Hadeler, Thomas Hillen, Frithjof Lutscher

Bibliographic record

VenueMathematical Models and Methods in Applied Sciences · 2004
Typearticle
Languageen
FieldMathematics
TopicMathematical Biology Tumor Growth
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsLangevin equationMoment (physics)Nonlinear systemVariable (mathematics)Partial differential equationStochastic differential equationSpace (punctuation)Mathematical analysisDiffusion equationPhysicsDiffusionMathematicsStatistical physicsDifferential equationClassical mechanics

Abstract

fetched live from OpenAlex

In the Langevin or Ornstein–Uhlenbeck approach to diffusion, stochastic increments are applied to the velocity rather than to the space variable. The density of this process satisfies a linear partial differential equation of the general form of a transport equation which is hyperbolic with respect to the space variable but parabolic with respect to the velocity variable, the Klein–Kramers or simply Kramers equation. This modeling approach allows for a more detailed description of individual movement and orientation dependent interaction than the frequently used reaction diffusion framework. For the Kramers equation, moments are computed, the infinite system of moment equations is closed at several levels, and telegraph and diffusion equations are derived as approximations. Then nonlinearities are introduced such that the semi-linear reaction Kramers equation describes particles which move and interact on the same time-scale. Also for these nonlinear problems a moment approach is feasible and yields nonlinear damped wave equations as limiting cases. We apply the moment method to the Kramers equation for chemotactic movement and obtain the classical Patlak–Keller–Segel model. We discuss similarities between chemotactic movement of bacteria and gravitational movement of physical particles.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.012

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.001
Science and technology studies0.0010.002
Scholarly communication0.0020.003
Open science0.0020.001
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.316
GPT teacher head0.453
Teacher spread0.137 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations32
Published2004
Admission routes1
Has abstractyes

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Same venueMathematical Models and Methods in Applied SciencesSame topicMathematical Biology Tumor GrowthFrench-language works237,207