Management of Community-acquired Pneumonia in Adults
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Objective: To revise the existing South African community-acquired pneumonia guideline in the light of the following factors: • Increasing antibiotic resistance • Introduction of new antibiotics • International trends based on evidence published since the previous guideline The main aim of the guideline is to recommend an initial choice of antibiotics in patients with community-acquired pneumonia encompassing the following subgroups: (i) adults without co-morbid illness; (ii) the elderly and/or those with associated co-morbid illness, including patients with concomitant human immunodeficiency virus (HIV) infection; and (iii) patients with severe pneumonia Options: Studies comparing patient outcome obtained with the various treatment regimens have been reviewed. The choice of antibiotic is based on the most commonly isolated pathogens, with cost as a consideration. Outcomes: The empiric antibiotic therapy covers all commonly encountered organisms in patients with community-acquired pneumonia and is likely to achieve the best prognosis. Evidence: Working group of clinicians and clinical microbiologists, following detailed literature review, particularly of studies performed in South Africa. Benefits, harms and costs: The guideline pays particular attention to cost-effectiveness in South Africa and promotes rational antibiotic prescribing with the aim of limiting emergence of antibiotic resistance. Recommendations: These include details of likely pathogens, an appropriate diagnostic approach, indicators of severity of illness, need for hospitalization and antibiotic treatment options. Validation: The guideline was updated by a working group of the South African Thoracic Society, which included members of the Critical Care Society of Southern Africa, and the Federation of Infectious Diseases Societies of Southern Africa. Reference was made to the recently updated international guidelines from the UK, Europe, Canada and the USA. Endorsement: The guideline is endorsed by the South African Thoracic Society, the Federation of Infectious Diseases Societies of Southern Africa, and the Critical Care Society of Southern Africa.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it