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Chemistry with ADF

2001· article· en· 10,049 citations· W2150345533 on OpenAlex· 10.1002/jcc.1056

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Abstract

Abstract We present the theoretical and technical foundations of the Amsterdam Density Functional (ADF) program with a survey of the characteristics of the code (numerical integration, density fitting for the Coulomb potential, and STO basis functions). Recent developments enhance the efficiency of ADF (e.g., parallelization, near order‐N scaling, QM/MM) and its functionality (e.g., NMR chemical shifts, COSMO solvent effects, ZORA relativistic method, excitation energies, frequency‐dependent (hyper)polarizabilities, atomic VDD charges). In the Applications section we discuss the physical model of the electronic structure and the chemical bond, i.e., the Kohn–Sham molecular orbital (MO) theory, and illustrate the power of the Kohn–Sham MO model in conjunction with the ADF‐typical fragment approach to quantitatively understand and predict chemical phenomena. We review the “Activation‐strain TS interaction” (ATS) model of chemical reactivity as a conceptual framework for understanding how activation barriers of various types of (competing) reaction mechanisms arise and how they may be controlled, for example, in organic chemistry or homogeneous catalysis. Finally, we include a brief discussion of exemplary applications in the field of biochemistry (structure and bonding of DNA) and of time‐dependent density functional theory (TDDFT) to indicate how this development further reinforces the ADF tools for the analysis of chemical phenomena. © 2001 John Wiley & Sons, Inc. J Comput Chem 22: 931–967, 2001

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The record

Venue
Journal of Computational Chemistry
Topic
Advanced Chemical Physics Studies
Field
Physics and Astronomy
Canadian institutions
University of Calgary
Funders
Keywords
ChemistryDensity functional theoryTime-dependent density functional theoryScalingComputational chemistryReactivity (psychology)Chemical shiftCoulombSolvent effectsChemical bondHybrid functionalQuantum mechanicsPhysical chemistryPhysicsSolventOrganic chemistry
Has abstract in OpenAlex
yes