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Endothelial Cell Migration During Angiogenesis

2007· review· en· 1,506 citations· W2156713309 on OpenAlex· 10.1161/01.res.0000259593.07661.1e

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.143
GPT teacher head0.431
Teacher spread
0.288 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

Endothelial cell migration is essential to angiogenesis. This motile process is directionally regulated by chemotactic, haptotactic, and mechanotactic stimuli and further involves degradation of the extracellular matrix to enable progression of the migrating cells. It requires the activation of several signaling pathways that converge on cytoskeletal remodeling. Then, it follows a series of events in which the endothelial cells extend, contract, and throw their rear toward the front and progress forward. The aim of this review is to give an integrative view of the signaling mechanisms that govern endothelial cell migration in the context of angiogenesis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

The record

Venue
Circulation Research
Topic
Angiogenesis and VEGF in Cancer
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Université Laval
Funders
Keywords
AngiogenesisCell biologyExtracellular matrixChemotaxisCell migrationEndothelial stem cellContext (archaeology)BiologySignal transductionCytoskeletonCellNeuroscienceCancer researchBiochemistry
Has abstract in OpenAlex
yes