Increasing incidence of myasthenia gravis among elderly in British Columbia, Canada
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
Presence of anti-acetylcholine receptor (anti-AChR) antibodies is highly specific for myasthenia gravis (MG). These antibodies are detected in 85%–95% of sera from patients with generalized MG and 40%–70% of patients with ocular MG.1 An increasing incidence of MG, especially in the elderly population, has been described in Japan, the United Kingdom, and Denmark.2,–,4 Recent studies have also focused on the epidemiology of anti-AChR antibody seropositivity as a surrogate marker of MG.4,–,6 The Neuro-Immunology Laboratory at the University of British Columbia is the sole laboratory in British Columbia (BC), Canada, offering anti-AChR antibody testing for clinical diagnosis. The aims of this study were to evaluate the incidence and epidemiologic characteristics of anti-AChR antibody seropositivity in BC and to examine changes in incidence over time. ### Methods. We performed a population-based study of the incidence of anti-AChR antibody-seropositivity in BC for the 25-year period of January 1, 1984, to December 31, 2008. Incident cases were ascertained by retrospectively identifying all first-time seropositive tests. A positive anti-AChR antibody test …
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it