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The Evidence for Efficacy of HPV Vaccines: Investigations in Categorical Data Analysis

2013· article· en· W2188140823 on OpenAlexaff
Alison L. Gibbs, Emery T. Goossens

Bibliographic record

VenueJournal of Statistics Education · 2013
Typearticle
Languageen
FieldMedicine
TopicCervical Cancer and HPV Research
Canadian institutionsUniversity of Toronto
FundersNational Cancer InstituteCenters for Disease Control and Prevention
KeywordsCategorical variableBiostatisticsContingency tableContext (archaeology)Statistical inferenceLogistic regressionStatisticsStatistical hypothesis testingComputer scienceData sciencePsychologyMedicineEconometricsMathematicsPublic health

Abstract

fetched live from OpenAlex

Recent approval of HPV vaccines and their widespread provision to young women provide an interesting context to gain experience with the application of statistical methods in current research. We demonstrate how we have used data extracted from a meta-analysis examining the efficacy of HPV vaccines in clinical trials with students in applied statistics courses at both introductory and intermediate university levels. The data are suitable for various techniques in categorical data analysis including comparison of proportions, analysis of contingency tables, logistic regression and log-linear models. These data are relevant to all young people and, because of their health science context, can be used in courses in biostatistics or the health sciences as they allow for further discussion of metaanalyses and randomized controlled trials. We also discuss how we have used these data to promote discussion of statistical issues such as statistical versus practical significance, independence, and a common misconception involving the interpretation of p-values.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.405
metaresearch head score (Gemma)0.834
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.405
Threshold uncertainty score0.734

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.4050.834
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0050.014
Bibliometrics0.0130.025
Science and technology studies0.0020.011
Scholarly communication0.0070.010
Open science0.0040.005
Research integrity0.0040.008
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.183
GPT teacher head0.477
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2013
Admission routes1
Has abstractyes

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