Gene Transfer by Electroporation of Filamentous Fungi
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The fungi encompass an enormous array of species, ranging from microscopic uninucleate, unicellular forms to multinucleate, coenocytic, highly differentiated macroscopic morphological forms. The wealth of diversity provided by a wide variety of life cycles, the availability of asexual and sexual modes of reproduction, and the presence of both haploid and diploid phases of the life cycle add further dimensions to this fascinating group of eukaryotic microbes. The tremendous potential of various taxa of filamentous fungi for biotechnological applications has yet to be realized. The filamentous fungi are emerging as a source of suitable hosts for expression of mammalian and other eukaryotic genes to yield products of commercial interest. They are ideally suited to this end by virtue of their normal mode of nutrition, based on the capacity for secretion of degradative enzymes, instrumental in conversion of complex growth substrates into simpler, readily utilizable derivatives that are absorbed by the growing fungal hyphae. Several species of filamentous fungi are known to produce pharmaceuticals, antibiotics, metabolites, phytohormones, and other industrially important products. There is a great deal of interest in the potential for the use of filamentous fungi as biocontrol agents—as antagonists of other fungal phytopathogens, as bioherbicides and bioinsecticides.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it