Alzheimer’s Disease and Related Disorders Annual. 2000. Edited by Serge Gauthier, and Jeffery L. Cummings. Published by Martin Dunitz Ltd. 255 pages. C$102.00 approx.
Bibliographic record
Abstract
The field of dementia continues to grow at a substantially rapid rate.This growth in knowledge permeates all aspects of this field, from basic science to patient care.With such a rapid rate of growth it is imperative to put new information in perspective.T h e "Alzheimer's Disease and Related Disorders Annual" serves an important purpose, in summarizing the most current information on various types of dementias and provides some perspective in basic research, as well as clinical care.There are 11 chapters, each written by individuals with expertise in the field.These chapters are comprehensive for the range of new advances, and include information on: genetics of Alzheimer's disease, chromosome 17 and frontotemporal dementia, dementia with Lewy bodies, parkinsonism with dementia, subcortical vascular dementia, minimal cognitive impairment, functional aspects of dementia, neuropsychiatric manifestations of dementia, cholinesterase inhibitors in the treatment of dementia, hormonal therapies for Alzheimer's disease, and anti-inflammatory therapy for Alzheimer's disease.One of the major strengths of this book is that it is edited by two individuals with keen understanding of dementias.Individual chapters are concise, thorough, and have a comprehensive set of references.Not surprisingly, given that all aspects of dementia are in the developmental stages, some of the new data are controversial in their application.The search for genetic aspects of dementia will continue and, potentially, will lead to treatment of these diseases.Clinical criteria for diagnosis of various dementias and their treatments will undoubtedly continue to be refined, but for now, this book serves as an excellent summary of many aspects of dementias to date.Some of the chapters, however, have perspectives that do not coincide with others.It would have been helpful for the editors to put some of this information in context for readers without a deep sense of present controversies.Nonetheless, the present effort is a starting point for future yearbooks on discussions and reviews on many aspects of these complex and intellectually challenging diseases.This book should be of interest to basic scientists, clinicians, nurses, and other health care providers, particularly those involved in dementias.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.003 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.002 | 0.002 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.001 | 0.003 |
| Insufficient payload (model declined to judge) | 0.151 | 0.208 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".