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Record W2411113113 · doi:10.1385/1-59259-192-2:413

Computing with DNA

2003· article· en· W2411113113 on OpenAlexaff
Lila Kari, Laura F. Landweber

Bibliographic record

VenueHumana Press eBooks · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicDNA and Biological Computing
Canadian institutionsWestern University
Fundersnot available
KeywordsComputationComputer scienceElectronicsEngineeringElectrical engineeringAlgorithm

Abstract

fetched live from OpenAlex

A brief look at the history of humanity shows that since the earliest days people needed to count and compute, either for measuring the months and the seasons or for commerce and construction. The means used for performing calculations were whatever was available, and thus progressed gradually from manual (digits) to mechanical (abacus, mechanical adding engine), and from there on to electronic devices. Electronic computers are only the latest in a long chain of human efforts to use the best technology available for performing computations. Although it is true that their appearance, some 50 years ago, has revolutionized computing, electronic computers mark neither the beginning nor the end of the history of computation. Indeed, even electronic computers have their limitations: There is a limit to the amount of data they can store, and physical laws dictate the speed thresholds they will soon reach. The most recent attempt to break down these barriers is to replace, once more, the tools for performing computations with biological ones instead of electrical ones. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.026
Threshold uncertainty score0.088

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.008
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0020.002
Science and technology studies0.0020.004
Scholarly communication0.0050.010
Open science0.0010.003
Research integrity0.0020.003
Insufficient payload (model declined to judge)0.0260.013

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.252
Teacher spread0.217 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2003
Admission routes1
Has abstractyes

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