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Record W2559115594

Proteome Analyst: An Overview

2004· article· en· W2559115594 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMachine Learning in Bioinformatics
Canadian institutionsUniversity of Alberta
Fundersnot available
KeywordsGene ontologyComputer scienceUploadParsingUniProtProteomeOntologyClassifier (UML)Set (abstract data type)Function (biology)Class (philosophy)Natural language processingComputational biologyArtificial intelligenceGeneBioinformaticsBiologyProgramming languageWorld Wide WebGenetics
DOInot available

Abstract

fetched live from OpenAlex

PA provides 2 main services: •Analysis ( ) •Upload sequences in fastA format •Process the sequences with tools (runs BLAST, Prosite) •Parse tokens from the tool’s output •Use tokens to predict the class of the protein (Ex. Hydrolase Activity, Cytoplasm) using Machine Learning. •Provide an Explanation ( ) for the prediction •Custom Classifer Creation ( ) •Upload Labeled sequences in fastA format •Process the sequences with tools (runs BLAST, Prosite) •Parse tokens from the tool’s output and use them to detect similarities within classes using Machine Learning. •Use detected similarities to classify new proteins with unknown properties. What does PA do? PA recently finished training a new Gene Ontology (GO) Function classifier. •12 Classes •102,225 sequence training set •Built using EBI’s GO mapping & the SwissProt database •Precision: 93% •Recall: 97% Also see Proteome Analyst’s Gene Ontology Poster Gene Ontology Function

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.375
Threshold uncertainty score0.291

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.021
GPT teacher head0.314
Teacher spread0.293 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Quick stats

Citations0
Published2004
Admission routes1
Has abstractyes

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