Improving Efficiency of Parameter Estimation in Case-Cohort Studies with Multivariate Failure Time Data
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
The case-cohort study design is an effective way to reduce cost of assembling and measuring expensive covariates in large cohort studies. Recently, several weighted estimators were proposed for the case-cohort design when multiple diseases are of interest. However, these existing weighted estimators do not make effective use of the covariate information available in the whole cohort. Furthermore, the auxiliary information for the expensive covariates, which may be available in the studies, cannot be incorporated directly. In this article, we propose a class of updated-estimators. We show that, by making effective use of the whole cohort information, the proposed updated-estimators are guaranteed to be more efficient than the existing weighted estimators asymptotically. Furthermore, they are flexible to incorporate the auxiliary information whenever available. The advantages of the proposed updated-estimators are demonstrated in simulation studies and a real data analysis.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.037 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it