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Record W2605557773 · doi:10.23907/2015.004

Morbid Obesity is Not a Risk Factor for the Development of Clinically Significant Coronary Artery Atherosclerosis

2015· article· en· W2605557773 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueAcademic Forensic Pathology · 2015
Typearticle
Languageen
FieldMedicine
TopicCardiovascular Function and Risk Factors
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMedicineSudden deathCoronary atherosclerosisAutopsyCardiologyObesityInternal medicineCause of deathRisk factorBody mass indexPopulationSudden cardiac deathCoronary arteriesArteryCoronary artery disease

Abstract

fetched live from OpenAlex

Morbid obesity represents a significant health problem to a large and growing segment of the industrialized world. The cardiovascular complications are numerous and include systemic and pulmonary hypertension, obesity cardiomyopathy, heart failure, left ventricular dilatation and hypertrophy, arrhythmias, and sudden cardiac death. Morbidly obese (MO) individuals who die suddenly and unexpectedly may not have significant coronary artery atherosclerosis or acutely lethal natural diseases at autopsy. In this way, forensic pathologists may be challenged to understand the mechanism of sudden death when the major anatomic finding is often limited to cardiomegaly with or without chamber dilatation and wall thickening. The death investigation files for a large metropolitan medical examiner department were the source of data in this case-control retrospective study. A total of 3863 cases met inclusion criteria. The following data were obtained: sex, age, cause of death, manner of death, weight in pounds, height in inches, body mass index, heart weight in grams, and coronary artery atherosclerosis (CAA) severity. A population of MO decedents (N = 1290) was identified, and sex- and age-matched case controls of non-obese decedents (N = 2573) were selected. The degree of CAA was recorded for all major vascular territories in both MO decedents and control cases, and there was no statistically significant difference in CAA between decedents in the MO group and the control group. These data illustrate that obesity is not a significant independent risk factor for CAA.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.140
Threshold uncertainty score0.529

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.092
GPT teacher head0.317
Teacher spread0.225 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it