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Record W2791567841 · doi:10.5858/2002-126-384a-pfic

Prognostic Factors in Cancer

2002· article· en· W2791567841 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueArchives of Pathology & Laboratory Medicine · 2002
Typearticle
Languageen
FieldMedicine
TopicMultiple and Secondary Primary Cancers
Canadian institutionsnot available
Fundersnot available
KeywordsCompendiumCancerDiseaseRelevance (law)MedicinePathologyHistoryInternal medicinePolitical science

Abstract

fetched live from OpenAlex

2nd ed, edited by Mary K. Gospodarowicz, Donald E. Henson, Robert V. P. Hutter, Brian O'Sullivan, Leslie H. Sobin, and Christian Wittekind, 809 pp, with illus, New York, NY, Wiley-Liss, 2001.Prognostic Factors in Cancer, second edition, is a concise and accessible compendium of essential information, abstracted from an enormous body of medical and scientific literature, about determinants of outcome in malignant disease. It is a distillation of the long-term efforts of the International Union Against Cancer to define those determinants from existing data and to put them into a framework that is relevant to clinical practice. Notwithstanding the incontrovertible data that extent of disease and histologic type of tumor are generally the most important indicators of outcome, broad overlap in outcomes of patients with tumors of like stage and type exist. Thus, the search for additional tumor-, site-, and patient-specific factors that can provide more accurate prediction of outcome and aid in clinical management of patients has been intense. This search has been fruitful but has generated an overwhelming volume of data. For the practicing pathologist assessing cancer specimens, such data are critically important, but the task of tracking and analyzing this rapidly expanding body of data is beyond the capabilities of most.This 800-page paperback volume organizes and summarizes current knowledge about prognostic factors in each major tumor site by topic and relevance. It does so in a manner that is straightforward and very user friendly, even for those completely uninitiated in this field. It also contains an excellent introductory section that deals with general principles of prognostic factor assessment, classification, measurement, and statistical analysis and of application to clinical decision-making and research.The site-specific sections cover the entire range of major cancer sites, including the brain, as well as cancer types, including both solid and liquid tumors. Concise epidemiologic summaries are provided. All relevant tumor-related and host-related factors are discussed and are organized in context of the strength of existing data. References are comprehensive and cited in the text. All chapters are heavily supplemented with helpful graphic presentations of information, and each ends with an appendix of summary tables that provide an at-a-glance summary of the factors discussed, stratifying them into 3 levels of import of validation: essential, additional, and new and promising. The book ends with a glossary of terms, common and specialized, that are frequently used (and not infrequently used incorrectly) in the field of prognostic factors.In summary, this book is a must-have for pathologists involved either in cancer diagnosis or cancer research. The multifaceted, multidisciplinary approach and the concise but comprehensive organization of Prognostic Factors in Cancer make it uniquely valuable to pathologists involved in the care of cancer patients. The book begins with a quote from Sir William Osler, once the chairman of the pathology department at McGill University: “Medicine is a science of uncertainty and an art of probability.” These words are especially applicable to cancer medicine, but it is fair to say that Prognostic Factors in Cancer does its part to help decrease the uncertainty.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.104
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.296
Teacher spread0.264 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it