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Record W2806528777 · doi:10.1101/333005

Generalization of the minimum covariance determinant algorithm for categorical and mixed data types

2018· preprint· en· W2806528777 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.
aboutThe title or abstract carries a Canadian signal from the geographic lexicon.

Bibliographic record

VenuebioRxiv (Cold Spring Harbor Laboratory) · 2018
Typepreprint
Languageen
FieldAgricultural and Biological Sciences
TopicSensory Analysis and Statistical Methods
Canadian institutionsHealth Sciences CentreSunnybrook Health Science CentreWestern UniversityUniversity of TorontoBaycrest Hospital
FundersNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchNational Institutes of HealthEisaiGovernment of OntarioBioClinicaU.S. Department of DefenseAlzheimer's Disease Neuroimaging InitiativeF. Hoffmann-La RocheBristol-Myers SquibbEli Lilly and CompanyStrongBiogenOntario Brain InstituteNational Institute on AgingAlzheimer's Association
KeywordsCategorical variableGeneralizationCovarianceData typeOrdinal dataMathematicsComputer scienceMahalanobis distanceAlgorithmArtificial intelligenceStatistics

Abstract

fetched live from OpenAlex

Abstract The minimum covariance determinant (MCD) algorithm is one of the most common techniques to detect anomalous or outlying observations. The MCD algorithm depends on two features of multivariate data: the determinant of a matrix (i.e., geometric mean of the eigenvalues) and Mahalanobis distances (MD). While the MCD algorithm is commonly used, and has many extensions, the MCD is limited to analyses of quantitative data and more specifically data assumed to be continuous. One reason why the MCD does not extend to other data types such as categorical or ordinal data is because there is not a well-defined MD for data types other than continuous data. To address the lack of MCD-like techniques for categorical or mixed data we present a generalization of the MCD. To do so, we rely on a multivariate technique called correspondence analysis (CA). Through CA we can define MD via singular vectors and also compute the determinant from CA’s eigenvalues. Here we define and illustrate a generalized MCD on categorical data and then show how our generalized MCD extends beyond categorical data to accommodate mixed data types (e.g., categorical, ordinal, and continuous). We illustrate this generalized MCD on data from two large scale projects: the Ontario Neurodegenerative Disease Research Initiative (ONDRI) and the Alzheimer’s Disease Neuroimaging Initiative (ADNI), with genetics (categorical), clinical instruments and surveys (categorical or ordinal), and neuroimaging (continuous) data. We also make R code and toy data available in order to illustrate our generalized MCD.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.659
Threshold uncertainty score0.360

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.052
GPT teacher head0.272
Teacher spread0.220 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it