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Record W2886298463 · doi:10.1016/s2215-0366(18)30269-4

Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis

2018· review· en· W2886298463 on OpenAlexfundno aff
Samuele Cortese, Nicoletta Adamo, Cinzia Del Giovane, Christina Mohr Jensen, Adrian Hayes, Sara Carucci, Lauren Atkinson, Luca Tessari, Tobias Banaschewski, David Coghill, Chris Hollis, Emily Simonoff, Alessandro Zuddas, Corrado Barbui, Marianna Purgato, Hans‐Christoph Steinhausen, Farhad Shokraneh, Jun Xia, Andrea Cipriani

Bibliographic record

VenueThe Lancet Psychiatry · 2018
Typereview
Languageen
FieldMedicine
TopicAttention Deficit Hyperactivity Disorder
Canadian institutionsnot available
FundersNIHR Nottingham Biomedical Research CentreSchool of Pharmacy, University College LondonState University of New York Upstate Medical UniversityUniversity of California, IrvineStony Brook UniversitySykehuset ØstfoldRegion SjællandRheinische Friedrich-Wilhelms-Universität BonnYancheng Teachers UniversityBen-Gurion University of the NegevKarolinska InstitutetUniversity of TorontoUniversitat de ValènciaBar-Ilan UniversityAlbert-Ludwigs-Universität FreiburgKing's College LondonUniversiteit van AmsterdamUniversity of SydneyUniversity of SouthamptonNational Institute for Health and Care ResearchUniversität zu KölnDalhousie UniversityUniversity of Texas Health Science Center at HoustonUniversità degli Studi di CagliariUniversity of South CarolinaEli Lilly and CompanyState University of New YorkVrije Universiteit AmsterdamPennsylvania State UniversityCincinnati Children's Hospital Medical CenterHarvard UniversityRadboud UniversiteitOhio State UniversityMcGill UniversityNational Institute of Mental HealthPenn State College of MedicineUniversität BaselBrandeis UniversityLehigh UniversityUniversity of WashingtonYork UniversityEmory UniversityUniversity of Connecticut Health CenterUniversity of Pennsylvania
KeywordsTolerabilityAttention deficit hyperactivity disorderMeta-analysisAtomoxetinePsychiatryMEDLINEMedicinePsychologyClinical psychologyMethylphenidateAdverse effectInternal medicine

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.031
metaresearch head score (Gemma)0.071
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Meta-analysis · Consensus signal: Meta-analysis
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.031
Threshold uncertainty score0.165

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0310.071
Meta-epidemiology (narrow)0.0030.002
Meta-epidemiology (broad)0.0230.042
Bibliometrics0.0110.010
Science and technology studies0.0010.001
Scholarly communication0.0040.002
Open science0.0030.002
Research integrity0.0020.002
Insufficient payload (model declined to judge)0.0040.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.088
GPT teacher head0.393
Teacher spread0.305 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designMeta-analysis
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1,333
Published2018
Admission routes1
Has abstractyes

Explore more

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