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A homing system targets therapeutic T cells to brain cancer

2018· article· en· 39 citations· W2890616344 on OpenAlex· 10.1038/s41586-018-0499-y

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.

Post-publication record

Nature
Retraction
Reason
Concerns/Issues about Data;Concerns/Issues about Image;Concerns/Issues about Results and/or Conclusions;Investigation by Journal/Publisher;Upgrade/Update of Prior Notice(s);
Date
2/20/2019 0:00
Flagged by OpenAlex?
Yes

Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature
Topic
CAR-T cell therapy research
Field
Medicine
Canadian institutions
University of TorontoUniversity of British Columbia
Funders
National Institute of Allergy and Infectious DiseasesNational Institute of Diabetes and Digestive and Kidney DiseasesNational Cancer InstituteNational Heart, Lung, and Blood InstituteNational Institutes of Health
Keywords
ALCAMHoming (biology)Cytotoxic T cellExtravasationCancer cellImmune systemCancer researchCell adhesion moleculeCell adhesionImmunotherapyCancer immunotherapyCell biologyChemistryCancerImmunologyCellBiologyMedicineIn vitroInternal medicineBiochemistry
Has abstract in OpenAlex
no