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The Arctic charr (Salvelinus alpinus) genome and transcriptome assembly

2018· article· en· 89 citations· W2892375143 on OpenAlex· 10.1371/journal.pone.0204076

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Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Post-publication record

Nature
Retraction
Reason
Error in Analyses;Error in Results and/or Conclusions;
Date
2/9/2021 0:00
Flagged by OpenAlex?
Yes

Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.

Abstract

Arctic charr have a circumpolar distribution, persevere under extreme environmental conditions, and reach ages unknown to most other salmonids. The Salvelinus genus is primarily composed of species with genomes that are structured more like the ancestral salmonid genome than most Oncorhynchus and Salmo species of sister genera. It is thought that this aspect of the genome may be important for local adaptation (due to increased recombination) and anadromy (the migration of fish from saltwater to freshwater). In this study, we describe the generation of a new genetic map, the sequencing and assembly of the Arctic charr genome (GenBank accession: GCF_002910315.2) using the newly created genetic map and a previous genetic map, and present several analyses of the Arctic charr genes and genome assembly. The newly generated genetic map consists of 8,574 unique genetic markers and is similar to previous genetic maps with the exception of three major structural differences. The N50, identified BUSCOs, repetitive DNA content, and total size of the Arctic charr assembled genome are all comparable to other assembled salmonid genomes. An analysis to identify orthologous genes revealed that a large number of orthologs could be identified between salmonids and many appear to have highly conserved gene expression profiles between species. Comparing orthologous gene expression profiles may give us a better insight into which genes are more likely to influence species specific phenotypes.

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The record

Venue
PLoS ONE
Topic
Genomics and Phylogenetic Studies
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Icy Waters (Canada)University of GuelphUniversity of VictoriaSimon Fraser UniversityFisheries and Oceans Canada
Funders
Fisheries and Oceans CanadaCompute CanadaNatural Sciences and Engineering Research Council of CanadaAtlantic Canada Opportunities AgencyMcGill University
Keywords
SalvelinusBiologyGenomeSalmoGeneticsEvolutionary biologyGeneTroutFishery
Has abstract in OpenAlex
yes