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Record W2904290041 · doi:10.1016/j.cogsys.2018.12.001

A novel machine learning approach for early detection of hepatocellular carcinoma patients

2018· article· en· W2904290041 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueCognitive Systems Research · 2018
Typearticle
Languageen
FieldHealth Professions
TopicArtificial Intelligence in Healthcare
Canadian institutionsUniversité du Québec à Montréal
Fundersnot available
KeywordsFeature selectionSupport vector machineHepatocellular carcinomaPreprocessorNormalization (sociology)Artificial intelligenceMachine learningComputer scienceLiver cancerData pre-processingSelection (genetic algorithm)Feature (linguistics)Genetic algorithmMedicineInternal medicine

Abstract

fetched live from OpenAlex

Liver cancer is quite common type of cancer among individuals worldwide. Hepatocellular carcinoma (HCC) is the malignancy of liver cancer. It has high impact on individual’s life and investigating it early can decline the number of annual deaths. This study proposes a new machine learning approach to detect HCC using 165 patients. Ten well-known machine learning algorithms are employed. In the preprocessing step, the normalization approach is used. The genetic algorithm coupled with stratified 5-fold cross-validation method is applied twice, first for parameter optimization and then for feature selection. In this work, support vector machine (SVM) (type C-SVC) with new 2level genetic optimizer (genetic training) and feature selection yielded the highest accuracy and F1-Score of 0.8849 and 0.8762 respectively. Our proposed model can be used to test the performance with huge database and aid the clinicians.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.005
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.798
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0040.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0020.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.386
GPT teacher head0.506
Teacher spread0.120 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it