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Record W2911222265 · doi:10.15173/sciential.v1i1.1909

Characterizing a new species of Nematoda using genetic and morphological analyses

2018· article· en· W2911222265 on OpenAlexaffvenueabout
Mostafa Mohammed Elsabagh, Kimberley J Dej

Bibliographic record

VenueSciential - McMaster Undergraduate Science Journal · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Aging, and Longevity in Model Organisms
Canadian institutionsMcMaster University
Fundersnot available
KeywordsBiologyPhylum18S ribosomal RNARibosomal RNAEvolutionary biologyMorphometricsCaenorhabditis elegansZoologyEcologyGeneGenetics

Abstract

fetched live from OpenAlex

Nematodes (Nematoda) are slim tubular worms ranging between 0.5 mm – 2 mm in length and 10 to 100 µm thick. They have effectively adapted to inhabit all regions of the Earth, but are most commonly found in soils, decomposing vegetation, and freshwater sources. Ceanorhabditis elegans (C. elegans), an important member of this phylum, is a valuable model system. Owing to its small, fully sequenced genome, it is typically used to model the development of some diseases, such as neurodegenerative diseases. Nematodes are highly diverse, with over 30,000 species having not yet been described. While C. elegans will continue to be the primary model species, the classification of previously unknown species is valuable as it allows for study of the evolutionary pathway leading to each species, behavior and instincts, and how such animals behave as parasites. This diversity is exciting, and Drs. Kimberly Dej and Bhagwati Gupta work with students to document new species. In the laboratory, we use morphological analysis of the mouth, the pharynx, and the tail, combined with data generated by sequencing the 18S small ribosomal subunit rRNA gene to explore and document these new species. Here, we discuss how it was determined that a unique specimen collected from the Hamilton, Ontario area was found to have features of multiple genera: Oscheius and Ceanoreabditis.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.024
Threshold uncertainty score0.049

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.057
GPT teacher head0.315
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes3
Has abstractyes

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