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Record W2977361415 · doi:10.1016/j.waojou.2019.100059

Aeroallergen sensitization and upper respiratory allergies among patients living in rural and urban areas: Real-life exploration of the hygiene hypothesis

2019· article· en· W2977361415 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueWorld Allergy Organization Journal · 2019
Typearticle
Languageen
FieldMedicine
TopicAllergic Rhinitis and Sensitization
Canadian institutionsUniversity of Alberta Hospital
Fundersnot available
KeywordsHygiene hypothesisAllergyMedicineAtopyHygieneEnvironmental healthIncidence (geometry)AeroallergenSensitizationImmunologyAsthmaAllergenPathology

Abstract

fetched live from OpenAlex

The number of people experiencing allergies has been increasing in the last decades. However, the increase in the global incidence of allergies observed is too fast and steady to be due to a genetic mutation. It may be due to environmental changes acting on some individual susceptibilities. According to what experts call “the hygiene theory”, the “excessive cleanliness” has been implied in reduced “microbial stimulation needed to enable normal development of the immune system”.1 Specialists in allergy and immunology explored this concept; it evolved into the broader notion that declining microbial exposure is a major causative factor in the increasing incidence of atopy in recent years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.613

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.201
Teacher spread0.190 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it