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Feasibility of Automated Vital Sign Instability Detection in Children Admitted to the Pediatric Intensive Care Unit

2019· article· en· W2999568707 on OpenAlexaff
Georg Seidel, Srinivas Murthy, Cheryl Peters, Philipp Rostalski, Matthias Görges

Bibliographic record

VenueComputing in Cardiology Conference · 2019
Typearticle
Languageen
FieldMedicine
TopicCardiac Arrest and Resuscitation
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsVital signsPediatric intensive care unitFalse positive paradoxMedicineNeonatal intensive care unitIntensive care unitHarmMedical emergencyEmergency medicineIntensive care medicinePediatricsComputer scienceMachine learningPsychology

Abstract

fetched live from OpenAlex

Children admitted to a Pediatric Intensive Care Unit (PICU) are at risk of deterioration, which can lead to a cardiac arrest if undetected. Outcomes after pediatric cardiac arrest remain poor, even for witnessed, inhospital events. Thus, early detection of deterioration is paramount; ideally long before the risk of harm increases. Vital signs trends of patients admitted to the PICU at BC Children’s Hospital were extracted from local outcomes registries (n=96). A rule-based algorithm (RBA) for detecting vital signs instabilities was developed; we did so in the expectation of enhancing clinician trust compared to black box approaches such as deep neural networks. Two PICU physicians provided expert classifications for episodes indicative of vital signs instability or their absence. The RBA’s best result generated 91.6% correct, 6% false negatives, and 3% false positives on the test data (n=29) showing promise for eventual application in a clinical setting. Future research is needed to refine the algorithm and implement it in clinical practice.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.022
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.007
Threshold uncertainty score0.018

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.022
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.302
Teacher spread0.278 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2019
Admission routes1
Has abstractyes

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