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Record W3002779531 · doi:10.1109/tcc.2020.2968893

DNA Similarity Search With Access Control Over Encrypted Cloud Data

2020· article· en· W3002779531 on OpenAlexaff
Guowen Xu, Hongwei Li, Hao Ren, Xiaodong Lin, Xuemin Shen

Bibliographic record

VenueIEEE Transactions on Cloud Computing · 2020
Typearticle
Languageen
FieldComputer Science
TopicCryptography and Data Security
Canadian institutionsUniversity of WaterlooUniversity of Guelph
FundersNational Natural Science Foundation of China
KeywordsComputer scienceEncryptionDNA computingCloud computingCluster analysisSimilarity (geometry)Data miningOutsourcingNearest neighbor searchTheoretical computer scienceAlgorithmComputer securityArtificial intelligenceImage (mathematics)

Abstract

fetched live from OpenAlex

DNA similarity search has been widely applied in human genomic studies including DNA marking, genomic sequencing and genetic disease prediction. Meanwhile, with the explosive growth of data, users are increasingly inclining to store DNA data on the cloud for saving local cost. However, the high sensitivity of DNA data has forced the government to strictly control its acquisition and utilization. One potential solution is to encrypt DNA data before outsourcing them to the cloud. Nevertheless, private DNA similarity query has been an active research issue, state-of-the-art results are still defective in security, functionality, and efficiency. In this article, we propose EFSS, an efficient and fine-grained similarity search scheme over encrypted DNA data. In specific, first, we design an approximation algorithm to efficiently calculate the edit distances between two sequences. Second, we put forward a novel Boolean search strategy to achieve complicated logic queries such as mixed “AND” and “NO” operations on genes. Third, data access control is also supported in our EFSS through a variant of polynomial based design. Moreover, the K-means clustering algorithm is exploited to further improve the efficiency of execution. In the end, security analysis and extensive experiments demonstrate the high performance of EFSS compared with existing schemes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.005
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.002
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.005
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0020.004
Open science0.0020.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.065
GPT teacher head0.303
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations33
Published2020
Admission routes1
Has abstractyes

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