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Record W3027044460 · doi:10.1097/yic.0000000000000314

Clinical advances in obsessive-compulsive disorder: a position statement by the International College of Obsessive-Compulsive Spectrum Disorders

2020· review· en· W3027044460 on OpenAlexaff
Naomi Fineberg, Eric Hollander, Stefano Pallanti, Susanne Walitza, Edna Grünblatt, Bernardo Dell’Osso, Umberto Albert, Daniel Geller, Vlasios Brakoulias, Y.C. Janardhan Reddy, Shyam Sundar Arumugham, Roseli Gedanke Shavitt, Lynne M. Drummond, Benedetta Grancini, Vera De Carlo, Eduardo Cinosi, Samuel R. Chamberlain, Konstantinos Ioannidis, Carolyn I. Rodríguez, Kabir Garg, David Castle, Michael Van Ameringen, Dan J. Stein, Lior Carmi, Joseph Zohar, José M. Menchón

Bibliographic record

VenueInternational Clinical Psychopharmacology · 2020
Typereview
Languageen
FieldPsychology
TopicObsessive-Compulsive Spectrum Disorders
Canadian institutionsMcMaster UniversityHamilton Health Sciences
FundersNational Institute of Child Health and Human DevelopmentNational Institute of Mental HealthEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentResearch for Patient Benefit ProgrammeServierThe Wellcome Trust DBT India AllianceUniversität ZürichPurdue UniversityWellcome TrustUniversity of SydneyAllerganTeva Pharmaceutical IndustriesDepartment of Health and Social CareIndian Council of Medical ResearchDepartment of Biotechnology, Ministry of Science and Technology, IndiaPfizerLivaNovaPurdue PharmaEli Lilly and CompanyU.S. Department of DefenseWestern Sydney Local Health DistrictNational Institute for Health and Care ResearchBrainsWayH. Lundbeck A/SWestern Sydney UniversityEuropean College of NeuropsychopharmacologyNeurocrine Biosciences
KeywordsPosition statementObsessive compulsiveNeurostimulationPsychotherapistIntervention (counseling)PsychologyPosition paperPsychological interventionEvidence-based practiceClinical psychologyPsychiatryMedicineAlternative medicineFamily medicineNeuroscience

Abstract

fetched live from OpenAlex

In this position statement, developed by The International College of Obsessive-Compulsive Spectrum Disorders, a group of international experts responds to recent developments in the evidence-based management of obsessive-compulsive disorder (OCD). The article presents those selected therapeutic advances judged to be of utmost relevance to the treatment of OCD, based on new and emerging evidence from clinical and translational science. Areas covered include refinement in the methods of clinical assessment, the importance of early intervention based on new staging models and the need to provide sustained well-being involving effective relapse prevention. The relative benefits of psychological, pharmacological and somatic treatments are reviewed and novel treatment strategies for difficult to treat OCD, including neurostimulation, as well as new areas for research such as problematic internet use, novel digital interventions, immunological therapies, pharmacogenetics and novel forms of psychotherapy are discussed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.002
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: Review
Teacher disagreement score0.003
Threshold uncertainty score0.014

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.002
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0030.003
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0010.002
Research integrity0.0030.004
Insufficient payload (model declined to judge)0.0030.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.035
GPT teacher head0.460
Teacher spread0.425 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations152
Published2020
Admission routes1
Has abstractyes

Explore more

Same venueInternational Clinical PsychopharmacologySame topicObsessive-Compulsive Spectrum DisordersFrench-language works237,207