[Retracted] Association between Rosacea and Cardiovascular Diseases and Related Risk Factors: A Systematic Review and Meta‐Analysis
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.
Post-publication record
- Nature
- Retraction
- Reason
- Concerns/Issues about Data;Concerns/Issues about Article;Concerns/Issues about Referencing/Attributions;Concerns/Issues about Peer Review;Investigation by Journal/Publisher;Unreliable Results and/or Conclusions;
- Date
- 3/20/2024 0:00
- Flagged by OpenAlex?
- Yes
Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.
Abstract
Background . Rosacea is a common inflammatory skin disorder. Several studies, but not all, have suggested a high prevalence of cardiovascular diseases (CVDs) in rosacea patients. This study is aimed at investigating the association between rosacea and CVDs and related risk factors. Methods . We performed a literature search through PubMed, Embase, and Web of Science databases, from their respective inception to December 21, 2019. Two reviewers independently screened the articles, extracted data, and performed analysis, following the PRISMA guidelines. Odds ratios (OR) or standardized mean differences (SMD) and 95% confidence intervals (CI) were calculated for outcomes. The included studies’ quality was evaluated using the Newcastle Ottawa Scale (NOS). Results . The final meta‐analysis included ten studies. The pooled analysis found no association between rosacea prevalence and the incidence of CVDs (OR 0.97; 95% CI 0.86‐1.10). Rosacea was found to be significantly associated with several risk factors for CVDs (OR 1.17; 95% CI 1.05‐1.31), including hypertension (OR 1.17; 95% CI 1.02‐1.35), dyslipidemia (OR 1.34; 95% CI 1.00‐1.79), and metabolic syndrome (OR 1.72; 95% CI 1.09‐2.72). However, no association was found between rosacea and diabetes mellitus (OR 0.98; 95% CI 0.82‐1.16). Among the biological parameters, a significant association was found between rosacea and total cholesterol (SMD = 0.40; 95% CI = −0.00, 0.81; p < 0.05), low‐density lipoprotein cholesterol (SMD = 0.28; 95% CI = 0.01, 0.56; p < 0.05), and C‐reactive protein (CRP) (SMD = 0.25; 95% CI = 0.10, 0.41; p < 0.05). We found no association between rosacea and high‐density lipoprotein cholesterol (SMD = 0.00; 95% CI = −0.18, 0.18; p = 0.968) or triglycerides (SMD = 0.10; 95% CI = −0.04, 0.24; p = 0.171). Conclusions . Although no significant association was found between rosacea and CVDs, rosacea was found to be associated with several of related risk factors. Patients with rosacea should pay more attention to identifiable CVD risk factors, especially those related to inflammatory and metabolic disorders.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- BioMed Research International
- Topic
- Acne and Rosacea Treatments and Effects
- Field
- Medicine
- Canadian institutions
- —
- Funders
- —
- Keywords
- RosaceaMedicineDyslipidemiaOdds ratioInternal medicineMeta-analysisMetabolic syndromeConfidence intervalDiabetes mellitusIncidence (geometry)Cochrane LibraryGastroenterologyDermatologyAcneObesityEndocrinology
- Has abstract in OpenAlex
- yes