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Record W3106819668 · doi:10.1109/access.2020.3040486

3D CNN Design for the Classification of Alzheimer’s Disease Using Brain MRI and PET

2020· article· en· W3106819668 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

fundA Canadian funder is recorded on the work.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueIEEE Access · 2020
Typearticle
Languageen
FieldNeuroscience
TopicBrain Tumor Detection and Classification
Canadian institutionsnot available
FundersNational Institute on AgingNational Institute of Biomedical Imaging and BioengineeringCanadian Institutes of Health ResearchNational Institutes of HealthGenentechIXICOH. Lundbeck A/SServierEisaiMeso Scale DiagnosticsNational Research Foundation of KoreaNational Research FoundationNorthern California Institute for Research and EducationEli Lilly and CompanyU.S. Department of DefenseAlzheimer's Disease Neuroimaging InitiativeF. Hoffmann-La RocheUniversity of Southern CaliforniaPfizerBioClinicaBiogenMinistry of Science and ICT, South KoreaNovartis Pharmaceuticals CorporationBristol-Myers SquibbFoundation for the National Institutes of Health
KeywordsComputer scienceConvolutional neural networkArtificial intelligencePattern recognition (psychology)Deep learningFeature extractionFeature selectionFeature (linguistics)Redundancy (engineering)Kernel (algebra)Contextual image classificationMachine learningImage (mathematics)

Abstract

fetched live from OpenAlex

Attempt to diagnose Alzheimer's disease (AD) using imaging modalities is one of the scopes of deep learning. While considering the theoretical background from past studies, we are trying to identify convolutional neural network (CNN) behaviors moving from 2D to 3D architecture. This study aims to explore the output from a variety of CNN models implemented in the MRI or/and PET classification tasks for AD prediction while trying to summarize its characteristics with a variety of parameters that are tuned and changed. There are many architectures available; however, we are testing a basic architecture with a change in the reception area based on the convolutional layer's kernel size and its strides. The architecture has been categorized as converging, diverging, or equivalent if the filter kernel size is unchanged. This investigation studies a simple encoder based CNN with a sequential flow of features from low-level to high-level feature extraction. The idea is to present a diverging reception area by increasing the filter size and stride from a lower to a higher level. As a result, the feature redundancy is reduced and the trivial features keep on diminishing. The proposed architecture is referred to as `divNet', and several experiments were performed to determine how effective the architecture is in terms of the consumed memory, the number of parameters, running time, classification error, and the generalization error. This study surveys several related experiments by changing the hyper-parameters setting, the architecture selection based on the depth and area of the reception feature, and the data size.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.795
Threshold uncertainty score0.252

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.290
GPT teacher head0.374
Teacher spread0.085 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it