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Record W3132753049 · doi:10.1115/imece2020-24485

Toxicity of Nanoparticles Used in Minimum Quantity Lubrication (MQL) Machining: A Sustainability Analysis

2020· article· en· W3132753049 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueVolume 2A: Advanced Manufacturing · 2020
Typearticle
Languageen
FieldMedicine
TopicOrthopaedic implants and arthroplasty
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsToxicityNanoparticleLubricationAbrasion (mechanical)Materials scienceMachiningNanocompositeNanotechnologyChemistryMetallurgyComposite materialOrganic chemistry

Abstract

fetched live from OpenAlex

Abstract Minimum quantity lubrication (MQL) with nanocomposite particles is among the new areas of study and has proven to provide very good cooling and lubrication in the machining of difficult to cut materials, such as titanium, Inconel and ADI. It is therefore imperative to understand their effects on the environment in the early stages of investigation, prior to their wide scale usage in industry. This study focuses on the different nanocomposite particles used in previous research, which is available in the literature, and evaluates their sustainability characteristics by investigating the toxicity of these nanocomposite particles on humans. The cooling capabilities of each of the nanoparticles considered is first established from the existing literature and summarized. Human cell viability measured from in vitro toxicity studies of nanoparticles is used as a variable to easily capture the toxicity of nanoparticles. Six different human cell lines were chosen to represent the effects of possible exposure through inhalation [human lung epithelial cells (A549), and bronchial epithelial cells (NL-20)], ingestion (AGS, and HepG2) and dermal contact (THP-1, and human peripheral blood cells). A comparison table was developed (Table 2.0), which provides easy interpretation of the toxicity levels of the five nanoparticles that were considered using all three human cell lines. The drawback of this comparison is the lack of sufficient data to assign conclusive toxicity levels to the nanoparticles. The toxicity studies of nanoparticles on humans is still in its infancy and contradictory results exist for some of the nanoparticles. This is the first attempt to combine the results of the experimental investigations of nano-MQL cooling and the toxicity studies of nanoparticles, allowing researchers to make informed decisions in the selection of the most sustainable nanoparticles in the nano-MQL machining process.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.175
Threshold uncertainty score0.735

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.274
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it