RETRACTED: Toxicological Screening of 4-Phenyl-3,4-dihydrobenzo[<i>h</i>]quinolin-2(1<i>H</i>)-one: A New Potential Candidate for Alzheimer’s Treatment
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Post-publication record
- Nature
- Retraction
- Reason
- Duplication of/in Image;Unreliable Results and/or Conclusions;
- Date
- 9/6/2024 0:00
- Flagged by OpenAlex?
- Yes
Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement — it reports them as false, which reads as “fine”.
Abstract
of SF3 was higher than 2000 mg/kg. In acute and subacute studies, levels of alkaline phosphates and aspartate transaminase were increased. Teratogenicity showed no resorptions, no skeletal or soft tissue abnormalities, and no cleft pallet. Oxidative stress biomarkers were close to the normal, and no increase in the malondialdehyde level was seen. Histopathological studies revealed normal tissue architecture of the selected organs, except kidney, in acute oral and subacute toxicity studies at 40 mg/kg. The study concluded that SF3 is safer if used as a drug.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- ACS Omega
- Topic
- Cholinesterase and Neurodegenerative Diseases
- Field
- Medicine
- Canadian institutions
- University of Windsor
- Funders
- Universiti Malaya
- Keywords
- NaphthaleneBicyclic moleculeChemistryDerivative (finance)StereochemistryPharmacologyCombinatorial chemistryMedicinal chemistryOrganic chemistryMedicine
- Has abstract in OpenAlex
- yes