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Doença inflamatória intestinal: Revisão

2021· article· en· W4200116115 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenuePubVet · 2021
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineGastroenterology

Abstract

fetched live from OpenAlex

Inflammatory Bowel Disease (IBD) denotes a chronic illness of the gastrointestinal tract, characterized by persistent or recurrent clinical signs such as diarrhea, vomiting, loss of appetite and progressive weight loss. The IBD affects mainly middle aged dogs and cats, with no preference for gender. Although not having a clear etiology, most studies present it as a multifactorial disease, involving an exaggerated inflammatory immunological response against microbiota bacterias or antigens in dietary composition, with which the animal organism is not well adapted. The abnormal bacteria growth also seems to be related to IBD development. Specific dog breeds such as German Shepherd, West Highland White Terrier, Labrador, Basenji, Shar Pei and Poodle have a genetic predisposition to IBD, but it is not well elucidated. The diagnosis is established through the identification of the chronic gastrointestinal signs and the analysis both for image findings and biopsy histopathology. Some of the differential diagnosis of IBD includes giardiasis, linfoma, dietary hypersensitivity, E. coli infection and exocrine pancreatic insufficiency, that must be discarded with complementary exams. The treatment for IBD normally involves dietary changes and prescribed medications such as antibiotics and immunosuppressive drugs. The use of antibiotics is justified by the fact that bacterial antigens might be implicated in IBD etiology, but also because secondary bacterial development often occurs. Some authors argue the exclusive use of dietary therapy, because in some patients only this change can lead to parcial ou complete remission of the symptoms. There aren't studies about IBD prevention, because of its genetic etiology, but for the animal that has been already diagnosed with the disease there are some protocols to be followed, such as the use of hypoallergenic animal food, prebiotics, probiotics and synbiotics.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.623
Threshold uncertainty score0.487

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.238
Teacher spread0.231 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it