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Record W4224274179 · doi:10.1117/12.2628030

Prediction of Hepatitis C based on liver function test features

2022· article· en· W4224274179 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueInternational Conference on Statistics, Applied Mathematics, and Computing Science (CSAMCS 2021) · 2022
Typearticle
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsHepatitisHepatitis CLiver diseaseMedicineTest (biology)Liver function testsAcute hepatitisLiver functionCorrelationBlood testArtificial intelligenceInternal medicineHepatitis AHepatitis BAlgorithmGastroenterologyMathematicsComputer scienceBiology

Abstract

fetched live from OpenAlex

Hepatitis C is a widespread liver disease that possibly leads to serious symptoms if not diagnosed in time. Currently, several methods are already available for specific screening of Hepatitis C. However, their expensive costs make it hard to allow their broad use in countries with poor conditions. Here, by constructing a mathematical model, we introduce a new method for testing Hepatitis C diagnosis. Our method is based on the results of liver function tests; therefore, it is relatively more cost-saving to do the test. A study was conducted based on the dataset obtained from the UCI Machine Learning Repository at June 10, 2020, containing laboratory values of blood donors and Hepatitis C patients and demographic values like age. χ<sup>2</sup> and ANOVA test was used to find the correlation between Hepatitis C and parameters of liver function test. Logistics regression was used to build the model for the prediction of Hepatitis C. The result shows that there’s a significant increase in likelihood of Hepatitis C when there’s increase in AST (β = 0.09, p &lt; 0.001) and BIL (β = 0.057, p &lt; 0.01); and there’s also a significant decrease in likelihood of Hepatitis C when there’s increase in ALT (β = -0.026, p &lt; 0.001) and CHOL (β

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.960
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.310
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it