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Record W4224274179 · doi:10.1117/12.2628030

Prediction of Hepatitis C based on liver function test features

2022· article· en· W4224274179 on OpenAlexaff
Yuqi Huang, Danni Yang, Xinyi Zhang

Bibliographic record

VenueInternational Conference on Statistics, Applied Mathematics, and Computing Science (CSAMCS 2021) · 2022
Typearticle
Languageen
FieldMedicine
TopicHepatitis C virus research
Canadian institutionsUniversity of Waterloo
Fundersnot available
KeywordsHepatitisHepatitis CLiver diseaseMedicineTest (biology)Liver function testsAcute hepatitisLiver functionCorrelationBlood testArtificial intelligenceInternal medicineHepatitis AHepatitis BAlgorithmGastroenterologyMathematicsComputer scienceBiology

Abstract

fetched live from OpenAlex

Hepatitis C is a widespread liver disease that possibly leads to serious symptoms if not diagnosed in time. Currently, several methods are already available for specific screening of Hepatitis C. However, their expensive costs make it hard to allow their broad use in countries with poor conditions. Here, by constructing a mathematical model, we introduce a new method for testing Hepatitis C diagnosis. Our method is based on the results of liver function tests; therefore, it is relatively more cost-saving to do the test. A study was conducted based on the dataset obtained from the UCI Machine Learning Repository at June 10, 2020, containing laboratory values of blood donors and Hepatitis C patients and demographic values like age. χ2 and ANOVA test was used to find the correlation between Hepatitis C and parameters of liver function test. Logistics regression was used to build the model for the prediction of Hepatitis C. The result shows that there’s a significant increase in likelihood of Hepatitis C when there’s increase in AST (β = 0.09, p < 0.001) and BIL (β = 0.057, p < 0.01); and there’s also a significant decrease in likelihood of Hepatitis C when there’s increase in ALT (β = -0.026, p < 0.001) and CHOL (β

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.006
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Simulation or modeling · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.004
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.006
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.055
GPT teacher head0.310
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designSimulation or modeling
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2022
Admission routes1
Has abstractyes

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