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Record W4224285432 · doi:10.1117/12.2628105

Cox regression analysis on the survival rate of breast cancer patients

2022· article· en· W4224285432 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueInternational Conference on Statistics, Applied Mathematics, and Computing Science (CSAMCS 2021) · 2022
Typearticle
Languageen
FieldMedicine
TopicCancer Risks and Factors
Canadian institutionsnot available
Fundersnot available
KeywordsBreast cancerProportional hazards modelMedicineOncologyInternal medicineStage (stratigraphy)CancerSurvival analysisRegression analysisStatisticsBiology

Abstract

fetched live from OpenAlex

Limited studies have been conducted on the survival analysis of breast cancer patients. And no study has been investigated using cancer datasets from the UK and Canadian patients. This study aims to qualify the factors contributing to survival time for female breast cancer patients, including patients' age, tumor size, tumor stage, mutation counts, and positive lymph nodes. The hypothesis is proposed that these factors are all associated with the increasing death rate risk for breast cancer patients. The dataset comes from a study conducted on 2510 female breast cancer patients from the UK and Canada, collected by long-term clinical follow-up. The Cox model is applied to each factor to explore their relationship with the survival of patients. All the results are tested, using Schoenfeld residuals. The coefficients between the explanatory variables and survival time are 0.033863 for age, 0.064274 for lymph nodes, 0.007031 for tumor size, 0.010202 for mutation count, and 0.243451 for tumor stage. The C-index of this model is 0.65653558. Our study suggests that on the premise of having some clinical symptoms, the Cox model can be used to predict the survival time of breast cancer patients. The study has some reference value with its convenient procedure and certain accuracy. According to the outcome of Cox regression, the most pivotal explanatory variables are age, lymph nodes examined positive, tumor size, and tumor stage. As these variables increase, the expectation of the survival time of the patients will decrease.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.913
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.329
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it