Brain structure and function changes in inflammatory bowel disease
Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
As the importance of the brain-gut axis in the pathobiology of inflammatory bowel disease (IBD) continues to evolve, a greater understanding of brain structure and functional connectivity (FC) is necessary. In this magnetic resonance imaging (MRI) study, we investigated differences in brain structure and in FC of brain regions in 111 participants with IBD (76 ulcerative colitis (UC) and 35 Crohn's disease (CD)) and 74 healthy controls (HC). Significant differences between IBD and HC were observed in the three analyses used (voxel based morphometry, region-of-interest, and independent component analysis) in brain regions of the default mode, cerebellar, and visual networks. Significant differences between IBD subtypes (UC, CD) were found. The results of the current study establish that a relationship between brain functional connectivity and the brain-gut axis exists in IBD.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it