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Record W4238295017 · doi:10.1007/978-1-4419-7771-7_11

Homostability

2010· book-chapter· en· W4238295017 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueEvolutionary Bioinformatics · 2010
Typebook-chapter
Languageen
FieldMathematics
TopicMathematical Dynamics and Fractals
Canadian institutionsQueen's University
Fundersnot available
KeywordsGenetic codeSpeed wobbleSequence (biology)Base pairRedundancy (engineering)Base (topology)DNACode (set theory)Evolutionary biologyBiologyGeneticsMathematicsComputer sciencePhysics

Abstract

fetched live from OpenAlex

Genetic information is ‘written’ by a variation in sequence on the one hand, and the physical stability of the double-stranded structure is determined by the base composition on the other hand. … DNA is found to consist of a number of homostability regions which come from homogenous base sequences consisting of 500 base pairs or more. … Biologically, it is hard … to believe that such regional homostability originates in a fundamental characteristic of the genetic code itself. It is quite plausible … that the homostability region plays an important part somewhere in the biological process within which the DNA is closely related. If so, then the evolutionary selective force can be considered to have fixed such regions of DNA. From the size of the homostability region, recombination might be one possible process which is aided by it. In any case, the wobble bases [in codons] must give the necessary redundancy to make a homostability region without spoiling the biological meaning of the genetic code.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Insufficient payload (model declined to judge)
Consensus categoriesInsufficient payload (model declined to judge)
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Other · Consensus signal: Other
Teacher disagreement score0.351
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.269
Teacher spread0.238 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it