MétaCan
Menu
← Back to cohort
Record W4310591998 · doi:10.1126/science.add8737

RETRACTED: Gradual emergence followed by exponential spread of the SARS-CoV-2 Omicron variant in Africa

2022· article· en· W4310591998 on OpenAlexaff
Carlo Fischer, Tongai Maponga, Anges Yadouléton, Nuro Abílio, Emmanuel Aboce, Praise Adewumi, Pedro Afonso, Jewelna Akorli, Soa Fy Andriamandimby, Latifa Anga, Yvonne Ashong, Mohamed Amine Beloufa, Aïcha Bensalem, Richard J. Birtles, Anicet Luc Magloire Boumba, Freddie Bwanga, Mike Chaponda, Paradzai Chibukira, R Matthew Chico, Justin Chileshe, Gershom Chongwe, Assana Cissé, Umberto D’Alessandro, Xavier de Lamballerie, Joana Morais, Fawzi Derrar, Ndongo Dia, Youssouf Diarra, Lassina Doumbia, Christian Drosten, Philippe Dussart, Richard Echodu, Yannik Eggers, Abdelmajid Eloualid, Ousmane Faye, Torsten Feldt, Anna Frühauf, Afiwa Halatoko, Pauliana-Vanessa Ilouga, Nália Ismael, Ronan Jambou, Sheikh Jarju, Antje Kamprad, Ben Katowa, John Kayiwa, Leonard Kingwara, Ousmane Koita, Vincent Lacoste, Adamou Lagaré, Olfert Landt, Sonia Etenna Lekana-Douki, Jean Bernard Lékana-Douki, Etuhole Iipumbu, Hugues Loemba, Julius J. Lutwama, Santou Mamadou, Issaka Maman, Brendon Manyisa, Pedro A. Martinez, Japhet Matoba, Lusia Mhuulu, Andrés Moreira‐Soto, Judy Mwangi, Nadine N ́dilimabaka, Charity Angella Nassuna, Mamadou Ousmane Ndiath, Emmanuel Nepolo, Richard Njouom, Jalal Nourlil, Steven Ger Nyanjom, Eddy Okoth Odari, Alfred Okeng, Jean Bienvenue Ouoba, Michael Owusu, Irene Owusu Donkor, Karabo Kristen Phadu, Richard Odame Phillips, Wolfgang Preiser, Vurayai Ruhanya, Fortune Salah, Sourakatou Salifou, Amadou Alpha Sall, Augustina Angelina Sylverken, Paul Alain Tagnouokam‐Ngoupo, Zékiba Tarnagda, Francis Olivier Tchikaya, Tafese Beyene Tufa, Jan Felix Drexler

Post-publication record

NatureRetraction
ReasonContamination of Cell Lines/Tissues;Contamination of Materials;Unreliable Results and/or Conclusions;
Date12/20/2022 0:00
Flagged by OpenAlex?Yes

Source: Retraction Watch, joined by DOI. OpenAlex records retraction as is_retracted, a boolean over a state space with at least four values, so it cannot express an expression of concern, a correction or a reinstatement; it reports them as false, which reads as “fine”.

Bibliographic record

VenueScience · 2022
Typearticle
Languageen
FieldMedicine
TopicSARS-CoV-2 and COVID-19 Research
Canadian institutionsUniversity of Ottawa
FundersNoguchi Memorial Institute for Medical Research, University of GhanaAfrican Academy of SciencesKwame Nkrumah University of Science and TechnologyNational Health Laboratory ServiceJomo Kenyatta University of Agriculture and TechnologyFreie Universität BerlinCentre International de Recherches Médicales de FrancevilleUniversity of GhanaWorld Health OrganizationDepartment of Science and Innovation, South AfricaEuropean and Developing Countries Clinical Trials PartnershipHeinrich-Heine-Universität DüsseldorfInyuvesi Yakwazulu-NataliUK Research and InnovationPoliomyelitis Research FoundationUniversity of Salford ManchesterUniversiteit StellenboschMedical Research CouncilLondon School of Hygiene and Tropical MedicineBill and Melinda Gates Foundation
KeywordsTropismSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)BiologyTransmission (telecommunications)VirologyGenomeTissue tropismGeneticsGeneVirusMedicineDisease

Abstract

fetched live from OpenAlex

The geographic and evolutionary origins of the SARS-CoV-2 Omicron variant (BA.1), which was first detected mid-November 2021 in Southern Africa, remain unknown. We tested 13,097 COVID-19 patients sampled between mid-2021 to early 2022 from 22 African countries for BA.1 by real-time RT-PCR. By November-December 2021, BA.1 had replaced the Delta variant in all African sub-regions following a South-North gradient, with a peak Rt of 4.1. Polymerase chain reaction and near-full genome sequencing data revealed genetically diverse Omicron ancestors already existed across Africa by August 2021. Mutations, altering viral tropism, replication and immune escape, gradually accumulated in the spike gene. Omicron ancestors were therefore present in several African countries months before Omicron dominated transmission. These data also indicate that travel bans are ineffective in the face of undetected and widespread infection.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.003
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesResearch integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Other · Consensus signal: none
Teacher disagreement score1.000
Threshold uncertainty score0.011

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.003
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0010.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.048
GPT teacher head0.335
Teacher spread0.287 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designNot applicable
Domainnot available
GenreOther

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2022
Admission routes1
Has abstractyes

Explore more

Same venueScience→Same topicSARS-CoV-2 and COVID-19 Research→French-language works237,207→